Volume 4, Issue 3 (Autumn 2017)                   johe 2017, 4(3): 8-16 | Back to browse issues page


XML Persian Abstract Print


1- MSc, in Occupational Health,Iran University of Medical Sciences, Tehran, Iran
2- MSc, in Occupational Health,Iran University of Medical Sciences, Tehran, Iran , Zabiolah.damiri@gmail.com
Abstract:   (5681 Views)

Background: clean room is an environment fully enclosed where parameters such as airborne particles under control and is requirement in the pharmaceutical industries to produce quality products. The aim of this study was to assessment and simulation of airflow and particle of clean room by CFD method in a pharmaceutical industry.
Materials and Methods: This study used an experimental study that was conducted at 2015 in the pharmaceutical industry. The methodology used in this study was to evaluate the level and number of particles in the clean room according to the standard ISO 14644 – 3. Also, air flow and particle in cleanroom with cleanness of class C was simulated with Computational Fluid Dynamics.
Results: The results showed that the path of particle movement and distribution of particles in the clean room completely depend on the shape of the flow and the pattern of air flow in the clean room. Furthermore, the results of the simulation showed that the particles in the clean room wall return particle removal efficiency of 70% at 0.5 and 5 microns.
 
Conclusion: There is equipment and a tool in a clean room effects on the airflow pattern. The results of simulation showed that the pattern of dispersion, air flow in the clean room is the most affected by the removal of particles.
 

Full-Text [PDF 1403 kb]   (2203 Downloads)    
Type of Study: Research Article | Subject: Chemical agents

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.