fa بررسی ارتباط بین غلظت تتراکلرواتیلن در هوای بازدم و سطوح مواجهه فردی در شاغلین خشکشویی سم شناسی Toxicology مقاله پژوهشي Research Article <p dir="RTL" style="text-align: justify;"><strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">مقدمه:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شرایطی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">که</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">پایش</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">محیط</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">کار</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">جهت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تعیین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">میزان</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">کافی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نباشد،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">اندازه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گیری</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ترکیبات</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">برخی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">متابولیت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ها</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">روش</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">کاربردی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">جهت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">پایش</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بیولوژیکی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">محسوب</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">می</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گردد</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">. </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">هدف</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">این</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تحقیق،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تعیین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ارتباط</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غلظت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تتراکلرواتیلن</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">میزان مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">فردی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شاغلین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">خشکشویی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ها</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بود</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">.</span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">روش</span></span></strong> <strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">کار</span></span></strong><strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">این</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مطالعه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">توصیفی</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> مقطعی </span></span><span style="background:white;"><span style="font-family:b mitra;"><span style="font-size:12.0pt;">که در سال 1396 انجام پذیرفت</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">،</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> علاوه بر جمع آوری </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">نمونه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">های</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">فردی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">12 نفر</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شاغلین،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نمونه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">های</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">محیط کار</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">خشکشویی ها </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">نیز به طور همزمان </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">مورد</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> بررسی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">قرار</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گرفت</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">. </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">اندازه</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">‌</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">گیری</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تتراکلرواتیلن</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">طریق</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تلفیق</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">روش</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">های</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> 1003 </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">&nbsp; 3704 </span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">NIOSH</span></span></span> &nbsp;<span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بعد</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بهینه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">سازی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">پارامترهای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تجزیه،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">با</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">استفاده</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">دستگاه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گازکروماتوگراف مجهز به آشکارساز</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">یونش شعله</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">‌</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">ای (</span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">FID</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">) </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">انجام</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گرفت</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">. </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"></span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">یافته</span></span></strong><strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">‌</span></span></strong><strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">ها</span></span></strong><strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">این</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مطالعه،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">سطوح</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">فردی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شاغلین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بالاتر</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">حدود</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مجاز</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شغلی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">پیشنهادی</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> (</span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">OEL-TWA‌</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">)</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غلظت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تتراکلرواتیلن</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نیز</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">از</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شاخص</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بیولوژیکی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> (</span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">BEI</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">) </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">ملی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">کشور</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بیشتر</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بود</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">. </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">نتایج</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مطالعه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نشان</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">داد</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در سطح معنی داری 05/0، بین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غلظت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تتراکلرواتیلن</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">میزان</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">فردی ارتباط</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">معنی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">داری</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">وجود</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">دارد</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> (0/046= </span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">p</span></span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> 0/66=</span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">r</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">). </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">همچنین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ارتباط</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">معنی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">داری</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غلظت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">محیطی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">با</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غلظت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> (0/003= </span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">p</span></span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> 0/59=</span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">r</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">) </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">سطوح</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">فردی</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> (0/001= </span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">p</span></span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">0/91=</span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">r</span></span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">) </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">به</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">دست</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">آمد</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">. </span></span><br> <strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">نتیجه</span></span></strong> <strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">گیری</span></span></strong><strong><span style="font-family:b mitra;"><span style="font-size:12.0pt;">:</span></span></strong> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نتایج</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نشان</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">داد</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">که</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">اندازه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گیری</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تتراکلرواتیلن</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی،</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">به</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">عنوان</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">یک</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نشانگر</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">زیستی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غیر</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تهاجمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">جهت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ارزیابی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">مواجهه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شغلی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">خشکشویی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ها</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">دارای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">اعتبار</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">کافی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">است</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">. </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">همچنین</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">صورت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بهینه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">سازی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">شرایط</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تجزیه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">ای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">دستگاه</span></span> <span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">GC-FID</span></span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تلفیق</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">روش</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">‌</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">های</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> 1003 </span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">و</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;"> 3704 </span></span><span dir="LTR"><span style="font-family:times new roman,serif;"><span style="font-size:10.0pt;">NIOSH</span></span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">می</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">توان</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">غلظت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">تتراکلرواتیلن</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">در</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">هوای</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">بازدمی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">را</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">با</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">حساسیت</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">قابل قبولی</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">اندازه</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">گیری</span></span> <span style="font-family:b mitra;"><span style="font-size:12.0pt;">نمود</span></span><span style="font-family:b mitra;"><span style="font-size:12.0pt;">.&nbsp;</span></span><br> &nbsp;</p> <p style="text-align: justify;"><strong>Background:</strong> When workplace air monitoring is not sufficient to determine the exposure levels, the determination of compounds and some metabolites in exhaled air and personal exposure levels is considered a practical method for biological monitoring. The aim of this study was to determine the relationship between the concentration of tetrachlorethylene in exhaled air and personal exposure levels in the dry cleaning workers<br> <strong>Methods:</strong> In this descriptive cross - sectional study was performed in 2017, in addition to the collecting samples of exhaled air and personal exposure of 12 workers, the ambient air samples of dry cleaning workplace were examined. Also the ambient air samples were studied simultaneously.&nbsp; Measurement of tetrachlorethylene in the exhaled air was performed using gas chromatograph equipped with flame ionization detector (FID) through an incorporation of 1003 and 3704 NIOSH methods and optimization of analysis parameters<span dir="RTL">.</span><br> <strong>Results: </strong>In this study, the personal exposure levels were above the recommended national occupational exposure limits (OEL-TWA), and tetrachlorethylene concentration in exhaled air of workers were above the biological exposure index (BEI) respectively. The results showed that there is a significant relationship between the concentration of tetrachlorethylene in exhaled air and personal exposure levels (r=0.66, P=0.046). Also, was obtained the significant relationship between the concentration of ambient air with exhaled air concentrations (r=0.59, P=0.003), and personal exposure levels (r=0.91, P<0.001) respectively<span dir="RTL">.</span><br> <strong>Conclusion:</strong> The results indicated that tetrachlorethylene measuring in the exhaled air as a non-invasive biomarker is valid enough for assessing occupational exposure in the dry cleanings<span dir="RTL">.</span> And also tetrachlorethylene concentration in exhaled air can be measured with high sensitivity through optimizing of analytical conditions in GC-FID system and the integration of 1003 and 3704 NIOSH methods.</p> تتراکلرواتیلن, خشکشویی, پایش بیولوژیک, هوای بازدم, نمونه برداری هوا Tetrachlorethylene, Dry cleaning, Biological monitoring, Exhaled air, Air sampling 1 7 http://johe.umsha.ac.ir/browse.php?a_code=A-10-41-3&slc_lang=fa&sid=1 Fatemeh Rostami فاطمه رستمی mu_rostami@yahoo.com 10031947532846006741 10031947532846006741 Yes Hamadan University of Medical Sciences دانشــگاه علــوم پزشــکی همــدان Mohamad Javad Assari محمد جواد عصاری Asari@umsha.ac.ir 10031947532846006742 10031947532846006742 No Hamadan University of Medical Sciences دانشــگاه علــوم پزشــکی همــدان Mohsen Aliabadi محسن علی آبادی mohsem.aliabadi@umsha.ac.ir 10031947532846006743 10031947532846006743 No Hamadan University of Medical Sciences دانشــگاه علــوم پزشــکی همــدان Maryam Farhadian مریم فرهادیان m.farhadian@umsha.ac.ir 10031947532846006744 10031947532846006744 No Hamadan University of Medical Sciences دانشــگاه علــوم پزشــکی همــدان